INCREDB ID : 200
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Kakoli Bose, Ph.D.
Principal Investigator 
 
Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre
Kharghar
Navi Mumbai - 410 210   
 
E-mail: kbose@actrec.gov.in
Phone: +91-22-2740 5109
Fax:  +91-22-2740 5085
 
Positions Held:
Position Affiliation Time Period
Post Doctoral Fellowship Tufts University School of Medicine, Boston, USA
 
Publications:
1. Wei, J., Liu, Y., Bose, K., Henry, G. D. and Baleja, J. D.  Disorder and structure in the Rab11 binding domain of Rab11 family interacting protein 2. Biochemistry. 2009.  48, 549-557. [PubMed]
2. Bose, K., Yoder, N. C., Kumar, K. and Baleja, J. D.  The role of conserved histidines in the structure and stability of human papillomavirus type 16 E2 DNA-binding domain. Biochemistry. 2007.  46, 1402-1411. [PubMed]
3. Bose, K. and Clark, A. C.  pH effects on the stability and dimerization of procaspase-3. Protein Science. 2005.  14, 24-36. [PubMed]
4. Bose, K., Pop, C., Feeney, B. and Clark, A. C.  An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3. Biochemistry. 2003.  42, 12298-12310. [PubMed]
5. Bose, K. and Clark, A. C.  Dimeric procaspase-3 unfolds via a four-state equilibrium process. Biochemistry. 2001.  40, 14236-14242. [PubMed]
6. Pop, C., Chen, Y. R., Smith, B., Bose, K., Bobay, B., Tripathy, A., Franzen, S. and Clark, A. C.  Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer. Biochemistry. 2001.  40, 14224-14235. [PubMed]
 

 
Grant Support:
Project Title Role Funding Agency Sanction Number Sanction Date
Structural Insights into Regulation of Proapoptotic HtrA2/Omi Protein; a Serine Protease with Multitasking Ability
Understanding Protein-Protein Interactions Involved in Papillomaviral E2 Induced Apoptosis

 
 
 
Education 
::
Ph.D. in Biochemistry, North Carolina State University, Department of Biochemistry, Raleigh, USA
Honors and Awards
::
Designed a papillomaviral inhibitor that is currently being developed by the Tufts University for Technology Transfer for turning it into a patent application and being evaluated by a company to license the technology
::
2005, Received Natalie Zucker Research Grant Award
::
2005, Received honorable mention in Tufts Dean’s letter
::
2002, Received award for best poster presentation in the Research Triangle Park Annual Conference on Biochemistry, NC
::
Obtained full Scholarship from NC State University for Doctoral study
Member
::
Member, American Chemical Society
::
Member, American Association for the Advancement of Science
::
Member, The Protein Society
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.