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Kapettu Satyamoorthy, Ph.D.
Manipal Life Sciences Centre, Manipal University
Phone: +91-820-2922058, 2922549
Fax: +91-820-2571919
Positions Held:
Position Affiliation Time Period
Director Manipal Life Sciences Centre, Manipal University, Manipal, India 2006-Present
Professor and Head Manipal Life Sciences Centre, Manipal University, Manipal, India 2002-Present
Senior Scientist The Wistar Institute, Philadelphia, USA 1994-2001
Area of Specialization:
Molecular Biology
Research Summary:
Eukaryotic transcription
Human genetics
1. Saadi, A. V., Girisha, K. M., Gopinath, P. M. and Satyamoorthy, K.  Analysis of cosegregation of intragenic DNA sequence variations as markers of maternal cell contamination in prenatal diagnosis of beta-thalassemia. Translational Research : the Journal of Laboratory and Clinical Medicine. 2011.  157, 150-155. [PubMed]
2. Kamalakaran, S., Varadan, V., Giercksky, R., Levy, D., Kendall, J., Janevski, A., Riggs, M., Banerjee, N., Synnestvedt, M., Schlichting, E., Karesen, R., Shama, P., Rotti, H., Rao, R., Rao, L., Eric, T., Satyamoorthy, K., Lucito, R., Wigler, M., Dimitrova, N., Naume, B., Borresen-Dale, A. L. and Hicks, J. B.  DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables. Molecular oncology. 2011.  5, 77-92. [PubMed]
3. Kumar, P., Bs, S. R., Kamath, S. D., Prabhu, V., Satyamoorthy, K. and Mahato, K. K.  Autofluorescence of Osteoporotic Mouse Femur Bones: A Pilot Study. Photomedicine and laser surgery. 2010.  [PubMed]
4. Satyanarayana, C., Devendran, A., Satyamoorthy, K., Shewade, D. G., Krishnamoorthy, R. and Chandrasekaran, A.  Functional characterization of promoter region polymorphisms of human CYP2C19 gene. Molecular biology reports. 2010.  [PubMed]
5. Rajender, S., Francis, A., Pooja, S., Krupakar, N., Surekha, D., Reddy, G., Rao, D. R., Rao, L., Ramachandra, S., Vishnupriya, S., Ramalingam, K., Satyamoorthy, K. and Thangaraj, K.  CAG repeat length polymorphism in the androgen receptor gene and breast cancer risk: data on Indian women and survey from the world. Breast cancer research and treatment. 2010.  [PubMed]
6. Girisha, K. M., Rajasekhar, M., Gopinath, P. M. and Satyamoorthy, K.  Balanced translocation in mother leading to interchange trisomy 21? Genetic counseling. 2010.  21, 183-185. [PubMed]
7. Sharma, M., Bairy, I., Pai, K., Satyamoorthy, K., Prasad, S., Berkovitz, B. and Radhakrishnan, R.  Salivary IL-6 levels in oral leukoplakia with dysplasia and its clinical relevance to tobacco habits and periodontitis. Clinical oral investigations. 2010.  [PubMed]
8. Roshan, M., Vijaya, P. H., Lavanya, G. R., Shama, P. K., Santhiya, S. T., Graw, J., Gopinath, P. M. and Satyamoorthy, K.  A novel human CRYGD mutation in a juvenile autosomal dominant cataract. Molecular vision. 2010.  16, 887-896. [PubMed]
9. Girisha, K. M., Vahab, S. A., Dalal, A. B., Gopinath, P. M. and Satyamoorthy, K.  Compound heterozygosity for HbD Punjab and polyadenylation signal mutation causes clinically asymptomatic mild hypochromia and microcytosis. Annals of hematology. 2010.  89, 625-626. [PubMed]
10. Dhanya Sunil, Arun M. Isloor, Prakash Shetty, Satyamoorthy, K., A.S. Bharath Prasad.  6-[3-(4-Fluorophenyl) - 1H-pyrazol-4-yl]- 3 - [(2-naphthyloxy) methyl][1,2,4] triazolo [3,4-b][1,3,4] - thiadiazole as a potent antioxidant and an anticancer agent induces growth inhibition followed by apoptosis in HepG2 cells. Arabian Journal of Chemistry.2010. 3: 211–217
11. Sumati Bhalla, Shobha Tandon, Satyamoorthy, K. 2010. Salivary proteins and early childhood caries: A gel electrophoretic analysis. Contemporary Clinical Dentistry. 1: 17-22.
12. Abdul Vahab Saadi, Pralhad Kushtagi, PM Gopinath and Satyamoorthy, K.  2010. Quantitative Fluorescence Polymerase Chain Reaction (QF-PCR) for prenatal diagnosis of chromosomal aneuploidies. Int. J. Hum Genet. 10: 121-129.
13. Raju Murugesan, Saadi Abdul Vahab, Satyajit Patra, Rekha Rao, Jyothi Rao, Padmalatha Rai, PM Gopinath and Satyamoorthy, K. 2010 Thiopurine S-methyltransferase alleles, TPMT*2, *3B and *3C, and genotype frequencies in an Indian population. Experimental and Therapeutic Medicine 1: 121-127
14. Vahab, S. A., Sen, S., Ravindran, N., Mony, S., Mathew, A., Vijayan, N., Nayak, G., Bhaskaranand, N., Banerjee, M. and Satyamoorthy, K.  Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population. Drug metabolism and pharmacokinetics. 2009.  24, 255-260. [PubMed]
15. Cyril, C., Rai, P., Chandra, N., Gopinath, P. M. and Satyamoorthy, K.  MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India. Indian journal of human genetics. 2009.  15, 60-64. [PubMed]
16. Bishen, K. A., Radhakrishnan, R. and Satyamoorthy, K.  The role of basic fibroblast growth factor in oral submucous fibrosis pathogenesis. Journal of oral pathology & medicine. 2008.  37, 402-411. [PubMed]
17. Radhakrishnan, R., Solomon, M., Satyamoorthy, K., Martin, L. E. and Lingen, M. W.  Tissue microarray - a high-throughput molecular analysis in head and neck cancer. Journal of oral pathology & medicine. 2008.  37, 166-176. [PubMed]
  Nadav Sega, Frank Andriani, Lawrence Pfeiffer, Padmaja Kamath, Nitin Lin, Satyamoorthy, K., Christophe Egles, Jonathan A. Garlick. 2008. The basement membrane microenvironment directs the normalization and survival of bioengineered human skin equivalents. Matrix Biology. 27: 163-170.
18. Valiathan, A., Sivakumar, A., Marianayagam, D., Valiathan, M. and Satyamoorthy, K.  Thurston syndrome: report of a new case. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2006.  101, 757-760. [PubMed]
19. Chidananda, S. M., Satyamoorthy, K., Rai, L., Manjunath, A. P. and Kartha, V. B.  Optical diagnosis of cervical cancer by fluorescence spectroscopy technique. International journal of cancer.  119, 139-145. [PubMed]
20. Meier, F., Schittek, B., Busch, S., Garbe, C., Smalley, K., Satyamoorthy, K., Li, G. and Herlyn, M.  The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Frontiers in bioscience. 2005.  10, 2986-3001. [PubMed]
21. Soltani, M. H., Pichardo, R., Song, Z., Sangha, N., Camacho, F., Satyamoorthy, K., Sangueza, O. P. and Setaluri, V.  Microtubule-associated protein 2, a marker of neuronal differentiation, induces mitotic defects, inhibits growth of melanoma cells, and predicts metastatic potential of cutaneous melanoma. The American journal of pathology. 2005.  166, 1841-1850. [PubMed]
22. McArdle, L., Rafferty, M. M., Satyamoorthy, K., Maelandsmo, G. M., Dervan, P. A., Herlyn, M. and Easty, D. J.  Microarray analysis of phosphatase gene expression in human melanoma. The British journal of dermatology. 2005.  152, 925-930. [PubMed]
23. Joshi, R., Kumar, M. S., Satyamoorthy, K., Unnikrisnan, M. K. and Mukherjee, T.  Free radical reactions and antioxidant activities of sesamol: pulse radiolytic and biochemical studies. Journal of agricultural and food chemistry. 2005.  53, 2696-2703. [PubMed]
24. Berking, C., Takemoto, R., Satyamoorthy, K., Shirakawa, T., Eskandarpour, M., Hansson, J., VanBelle, P. A., Elder, D. E. and Herlyn, M.  Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B. Cancer research. 2004.  64, 807-811. [PubMed]
25. Somasundaram, R., Satyamoorthy, K., Caputo, L., Yssel, H. and Herlyn, D.  Detection of HLA class II-dependent T helper antigen using antigen phage display. Clinical and experimental immunology. 2004.  135, 247-252. [PubMed]
26. Meier, F., Caroli, U., Satyamoorthy, K., Schittek, B., Bauer, J., Berking, C., Moller, H., Maczey, E., Rassner, G., Herlyn, M. and Garbe, C.  Fibroblast growth factor-2 but not Mel-CAM and/or beta3 integrin promotes progression of melanocytes to melanoma. Experimental dermatology. 2003.  12, 296-306. [PubMed]
27. Li, G., Satyamoorthy, K., Meier, F., Berking, C., Bogenrieder, T. and Herlyn, M.  Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil. Oncogene. 2003.  22, 3162-3171. [PubMed]
28. Satyamoorthy, K. and Herlyn, M.  p16INK4A and familial melanoma. Methods in molecular biology. 2003.  222, 185-195. [PubMed]
29. Gruss, C. J., Satyamoorthy, K., Berking, C., Lininger, J., Nesbit, M., Schaider, H., Liu, Z. J., Oka, M., Hsu, M. Y., Shirakawa, T., Li, G., Bogenrieder, T., Carmeliet, P., El-Deiry, W. S., Eck, S. L., Rao, J. S., Baker, A. H., Bennet, J. T., Crombleholme, T. M., Velazquez, O., Karmacharya, J., Margolis, D. J., Wilson, J. M., Detmar, M., Skobe, M., Robbins, P. D., Buck, C. and Herlyn, M.  Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. The Journal of investigative dermatology. 2003.  120, 683-692. [PubMed]
30. Satyamoorthy, K., Li, G., Gerrero, M. R., Brose, M. S., Volpe, P., Weber, B. L., Van, B., Elder, D. E. and Herlyn, M.  Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer research. 2003.  63, 756-759. [PubMed]
31. Zhang, H., Satyamoorthy, K., Herlyn, M. and Rosdahl, I.  All-trans retinoic acid (atRA) differentially induces apoptosis in matched primary and metastatic melanoma cells -- a speculation on damage effect of atRA via mitochondrial dysfunction and cell cycle redistribution. Carcinogenesis. 2003.  24, 185-191. [PubMed]
32. Schaider, H., Oka, M., Bogenrieder, T., Nesbit, M., Satyamoorthy, K., Berking, C., Matsushima, K. and Herlyn, M.  Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8. International journal of cancer. 2003.  103, 335-343. [PubMed]
33. Satyamoorthy, K., Li, G., Van, B., Elder, D. E. and Herlyn, M.  A versatile method for the removal of melanin from ribonucleic acids in melanocytic cells. Melanoma research. 2002.  12, 449-452. [PubMed]
34. Satyamoorthy, K. and Herlyn, M.  Cellular and molecular biology of human melanoma. Cancer biology & therapy. 2002.  1, 14-17. [PubMed]
35. Li, G., Satyamoorthy, K. and Herlyn, M.  Dynamics of cell interactions and communications during melanoma development. Critical reviews in oral biology and medicine. 2002.  13, 62-70. [PubMed]
36. Satyamoorthy, K., Li, G., Vaidya, B., Kalabis, J. and Herlyn, M.  Insulin-like growth factor-I-induced migration of melanoma cells is mediated by interleukin-8 induction. Cell growth & differentiation. 2002.  13, 87-93. [PubMed]
37. Sturm, R. A., Satyamoorthy, K., Meier, F., Gardiner, B. B., Smit, D. J., Vaidya, B. and Herlyn, M.  Osteonectin/SPARC induction by ectopic beta(3) integrin in human radial growth phase primary melanoma cells. Cancer research. 2002.  62, 226-232. [PubMed]
38. Li, G., Schaider, H., Satyamoorthy, K., Hanakawa, Y., Hashimoto, K. and Herlyn, M.  Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development. Oncogene. 2001.  20, 8125-8135. [PubMed]
39. Berking, C., Takemoto, R., Schaider, H., Showe, L., Satyamoorthy, K., Robbins, P. and Herlyn, M.  Transforming growth factor-beta1 increases survival of human melanoma through stroma remodeling. Cancer research. 2001.  61, 8306-8316. [PubMed]
40. Satyamoorthy, K., Li, G., Vaidya, B., Patel, D. and Herlyn, M.  Insulin-like growth factor-1 induces survival and growth of biologically early melanoma cells through both the mitogen-activated protein kinase and beta-catenin pathways. Cancer research. 2001.  61, 7318-7324. [PubMed]
41. Satyamoorthy, K., Muyrers, J., Meier, F., Patel, D. and Herlyn, M.  Mel-CAM-specific genetic suppressor elements inhibit melanoma growth and invasion through loss of gap junctional communication. Oncogene. 2001.  20, 4676-4684. [PubMed]
42. Li, G., Satyamoorthy, K. and Herlyn, M.  N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer research. 2001.  61, 3819-3825. [PubMed]
43. Satyamoorthy, K., Bogenrieder, T. and Herlyn, M.  No longer a molecular black box--new clues to apoptosis and drug resistance in melanoma. Trends in molecular medicine. 2001.  7, 191-194. [PubMed]
44. Berking, C., Takemoto, R., Satyamoorthy, K. Elenitsas, R. and Herlyn, M.  Basic fibroblast growth factor and ultraviolet B transform melanocytes in human skin. The American journal of pathology. 2001.  158, 943-953. [PubMed]
45. Satyamoorthy, K., Oka, M. and Herlyn, M.  An antisense strategy for inhibition of human melanoma growth targets the growth factor pleiotrophin. Pigment cell research. 2000.  13 Suppl 8, 87-93. [PubMed]
46. Satyamoorthy, K., Chehab, N. H., Waterman, M. J., Lien, M. C., El-Deiry, W. S., Herlyn, M. and Halazonetis, T. D.  Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells. Cell growth & differentiation. 2000.  11, 467-474. [PubMed]
47. Herlyn, M., Berking, C., Li, G. and Satyamoorthy, K.  Lessons from melanocyte development for understanding the biological events in naevus and melanoma formation. Melanoma research. 2000.  10, 303-312. [PubMed]
48. Oka, M., Berking, C., Nesbit, M., Satyamoorthy, K., Schaider, H., Murphy, G., Ichihashi, M., Sauter, E. and Herlyn, M.  Interleukin-8 overexpression is present in pyoderma gangrenosum ulcers and leads to ulcer formation in human skin xenografts. Laboratory investigation. 2000.  80, 595-604. [PubMed]
49. Satyamoorthy, K., Meier, F., Hsu, M. Y., Berking, C. and Herlyn, M.  Human xenografts, human skin and skin reconstructs for studies in melanoma development and progression. Cancer metastasis reviews. 1999.  18, 401-405. [PubMed]
50. Prabhu, N. S., Somasundaram, K., Tian, H., Enders, G. H., Satyamoorthy, K., Herlyn, M. and El-Deiry, W. S.  The administration schedule of cyclin-dependent kinase inhibitor gene therapy and etoposide chemotherapy is a major determinant of cytotoxicity. International journal of oncology. 1999.  15, 209-216. [PubMed]
51. Van, B., Elenitsas, R., Satyamoorthy, K., Wolfe, J. T., Guerry, D., Schuchter, L., Van, B., Albelda, S., Tahin, P., Herlyn, M. and Elder, D. E.  Progression-related expression of beta3 integrin in melanomas and nevi. Human pathology. 1999.  30, 562-567. [PubMed]
52. Mitra, J., Dai, C. Y., Somasundaram, K., El-Deiry, W. S., Satyamoorthy, K., Herlyn, M. and Enders, G. H.  Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a). Molecular and cellular biology. 1999.  19, 3916-3928. [PubMed]
53. Meier, F., Satyamoorthy, K., Nesbit, M., Hsu, M. Y., Schittek, B., Garbe, C. and Herlyn, M.  Molecular events in melanoma development and progression. Frontiers in bioscience. 1998.  3, D1005-10. [PubMed]
54. Prabhu, N. S., Somasundaram, K., Satyamoorthy, K., Herlyn, M. and El-Deiry, W. S.  p73beta, unlike p53, suppresses growth and induces apoptosis of human papillomavirus E6-expressing cancer cells. International journal of oncology. 1998.  13, 5-9. [PubMed]
55. Satyamoorthy, K., DeJesus, E., Linnenbach, A. J., Kraj, B., Kornreich, D. L., Rendle, S., Elder, D. E. and Herlyn, M.  Melanoma cell lines from different stages of progression and their biological and molecular analyses. Melanoma research. 1997.  7 Suppl 2, S35-42. [PubMed]
56. Satyamoorthy, K., Samulewicz, S. J., Thornburg, L. D., Basu, A. and Howe, C. C.  Identification of an intronic enhancer that nullifies upstream repression of SPARC gene expression. Nucleic acids research. 1997.  25, 3169-3174. [PubMed]
57. Satyamoorthy, K., Soballe, P. W., Soans, F. and Herlyn, M.  Adenovirus infection enhances killing of melanoma cells by a mitotoxin. Cancer research. 1997.  57, 1873-1876. [PubMed]
58. Satyamoorthy, K. and Howe, C. C.  The mouse elongation factor-2 gene: isolation and characterization of the promoter. DNA and cell biology. 1997.  16, 401-412. [PubMed]
59. Herlyn, M. and Satyamoorthy, K.  Activated ras. Yet another player in melanoma? The American journal of pathology. 1996.  149, 739-744. [PubMed]
60. Soballe, P. W., Montone, K. T., Satyamoorthy, K., Nesbit, M. and Herlyn, M.  Carcinogenesis in human skin grafted to SCID mice. Cancer research. 1996.  56, 757-764. [PubMed]
61. Kamat, J. P., Basu, A., Satyamoorthy, K., Xu, M. Q., Showe, L. and Howe, C. C.  IPEB transcription factor regulating the intracisternal A particle gene during F9 cell differentiation is expressed at sites of lymphoid development. Molecular reproduction and development. 1995.  41, 8-15. [PubMed]
62. Jain, N., Mittal, R., Srivastava, T.S., Satyamoorthy K., and Chitnis, M.P. 1994. Synthesis, characterization, DNA-binding, and cytotoxic studies of dinuclear complexes of Palladium(II) and Platinum(II) with 2,2-bipyridine and alpha, omega-diaminoalkane-N,N'-diacetic acid. J. Inorg. Biochem., 53: 79-94.
63.. Satyamoorthy, K., Park, K., Atchison, M. L. and Howe, C. C.  The intracisternal A-particle upstream element interacts with transcription factor YY1 to activate transcription: pleiotropic effects of YY1 on distinct DNA promoter elements. Molecular and cellular biology. 1993.  13, 6621-6628. [PubMed]
64. Lamb, B. T., Satyamoorthy, K., Solter, D., Basu, A., Xu, M. Q., Weinmann, R. and Howe, C. C.  A DNA element that regulates expression of an endogenous retrovirus during F9 cell differentiation is E1A dependent. Molecular and cellular biology. 1992.  12, 4824-4833. [PubMed]
65. Satyamoorthy, K., Perchellet, E. M. and Perchellet, J. P.  Effects of adriamycin and daunomycin on ornithine decarboxylase activity and DNA synthesis in mouse epidermal cells. Toxicology in vitro. 1992.  6, 459-463. [PubMed]
66. Lamb, B. T., Satyamoorthy, K., Li, L., Solter, D. and Howe, C. C.  CpG methylation of an endogenous retroviral enhancer inhibits transcription factor binding and activity. Gene expression. 1991.  1, 185-196. [PubMed]
67. Satyamoorthy, K. and Perchellet, J. P.  Inhibition of mouse skin tumor promotion by adriamycin and daunomycin in combination with verapamil or palmitoylcarnitine. Cancer letters. 1990.  55, 135-142. [PubMed]
68. Parekh, H., Satyamoorthy, K., Advani, S. and Chitnis, M.  Sensitization of chronic myeloid leukemia cells to adriamycin cytotoxicity by clofibrate. Tumori. 1990.  76, 18-21. [PubMed]
69. Satyamoorthy, K. and Perchellet, J. P.  Modulation by adriamycin, daunomycin, verapamil, and trifluoperazine of the biochemical processes linked to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer research. 1989.  49, 5364-5370. [PubMed]
70. Chitnis, M., Parekh, H. and Satyamoorthy, K.  Differential effect of clofibrate on adriamycin cytotoxicity in P388 murine leukemia cells sensitive and resistant to adriamycin. Tumori. 1989.  75, 100-105. [PubMed]
71. Kamath, N. S., Satyamoorthy, K., Chitnis, M. P. and Advani, S. H.  1,10-phenanthroline potentiates cytotoxicity of hydroxyurea in human chronic myeloid leukemia cells. Oncology. 1989.  46, 193-197. [PubMed]
72. Satyamoorthy, K., Chitnis, M. P., Pradhan, S. G. and Advani, S. H.  Modulation of mitoxantrone cytotoxicity by verapamil in human chronic myeloid leukemia cells. Oncology. 1989.  46, 128-131. [PubMed]
73. Satyamoorthy, K., Deshpande, S. S. and Chitnis, M. P.  Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro. Neoplasma. 1989.  36, 673-683. [PubMed]
74. Jain, N., Srivastava, T. S., Satyamoorthy, K. and Chitnis, M. P.  Synthesis, spectroscopic, and cytotoxicity studies of some diamine and diimine platinum(II) complexes of diethyldithiocarbamate. Journal of inorganic biochemistry. 1988.  33, 1-9. [PubMed]
75. Satyamoorthy, K. and Chitnis, M. P.  Hyperthermia blocks reversibility of hydroxyurea and bipyridine induced synergistic inhibition of DNA biosynthesis in P388 murine leukemia cells. Neoplasma. 1988.  35, 153-159. [PubMed]
76. Chitnis, M. P., Satyamoorthy, K., Pradhan, S. G. and Advani, S. H.  Modulation of sensitivity to mitoxantrone in human chronic myeloid leukemia cells by the antidepressant sintamil. Oncology. 1988.  45, 292-296. [PubMed]
77. Satyamoorthy, K., Chitnis, M. P. and Advani, S. H.  In vitro cytotoxicity of caracemide alone and in combination with hydroxyurea or iron-chelating agents in human chronic myeloid leukemia cells and murine tumors. Neoplasma. 1988.  35, 27-35. [PubMed]
78. Satyamoorthy, K. and Chitnis, M. P.  Effect of vitamin A compounds on DNA biosynthesis in murine tumor models in vitro. Oncology. 1987.  44, 356-359. [PubMed]
79. Chitnis, M. P., Pradhan, S. G., Satyamoorthy, K. and Basrur, V. S.  Restoration of drug sensitivity by nitroxazepine hydrochloride in P388 murine leukemia cells resistant to adriamycin. Cancer drug delivery. 1987.  4, 1-9. [PubMed]
80. Pradhan, S. G., Chitnis, M. P., Basrur, V. S., Satyamoorthy, K. and Advani, S. H.  Augmentation of hydroxyurea cytotoxicity by sintamil in human chronic myeloid leukemia cells. Tumori. 1986.  72, 507-510. [PubMed]
81. Satyamoorthy, K., Chitnis, M. and Basrur, V.  Sensitization of P388 murine leukemia cells to hydroxyurea cytotoxicity by hydrophobic iron-chelating agents. Anticancer research. 1986.  6, 329-333. [PubMed]
82. Satyamoorthy, K., Chitnis, M. P. and Pradhan, S. G.  Potentiation of hydroxyurea cytotoxicity by iron-chelating agent in murine tumor models in vitro. Cancer drug delivery. 1986.  3, 173-182. [PubMed]
83. Satyamoorthy, K., Chitnis, M. P., Basrur, V. S. and Advani, S. H.  Potentiation of hydroxyurea cytotoxicity in human chronic myeloid leukemia cells by iron-chelating agent. Leukemia research. 1986.  10, 1327-1330. [PubMed]
84. Chitnis, M., Menon, R., Adwankar, M. and Satyamoorthy, K.  Inhibition of macromolecular synthesis in P388 mouse leukemia ascites cells by bouvardin (NSC 259968). Tumori. 1985.  71, 261-266. [PubMed]
85. Chitnis, M. P., Menon, R. S., Basrur, V. S., Adwankar, M. K. and Satyamoorthy, K.  Reversal of natural resistance to bouvardin (NSC 259968) in sarcoma 180 cells in vitro and in vivo by verapamil. Journal of cancer research and clinical oncology. 1985.  110, 221-224. [PubMed]


Book Chapters:
Vahab, S. A., Patra, S. and Satyamoorthy, K. Pharmacogenomicsin Clinical Research. In: Rai R., and Bhat R. eds. Advances in Biotechnology. Narosa Publishers, New Delhi. pp1-26.
Satyamoorthy K. and Herlyn, M. 2002. Melanoma: Molecular and Cellular Abnormalities. In: J.R. Bertino, eds, Encyclopedia of Cancer. Academic Press. San Diego, CA. publishers, vol III, pp.131-139.
Herlyn,M and Sayamoorthy K. 2001. Molecular Biology of Cutaneous Melanoma. In: DeVita V.T., Hellman, S., and Rosenberg, S.A. eds, Cancer: Principles of Oncology, Lippincott Williams and Wilkins, publishers, pp. 2003-2012
Satyamoorthy K. and Herlyn, M. 1997. Melanoma: Molecular and Cellular Abnormalities. In: J.R. Bertino, eds., Encyclopedia of Cancer, Academic Press, CA publishersd, volume II, pp. 1042-1050.
Satyamoorthy K., Nesbit, M., Hsu, M.-Y., and Herlyn, M. 1996. Utility of adenoviruses as gene expression modules in melanoma. In: A. Maio eds., Immunology of Human Melanoma: Tumor-Host Interactions and Immunotherapy, IOS Press, CA, USA, publisher, pp. 71-77.
Chitnis, M.P., Basrur, V.S., Pradhan, S.G., and Satyamoorthy K. 1987. Biochemical mechanisms of drug resistance in cancer and its circumvention by drug response modulators. In: L. Lapis and S. Eckhardt, eds., Novel Approaches in Cancer Congress, Akademia Kiado, Budapest, publisher, vol. 5, pp. 135-140.
M.Sc. in Biochemistry, Bombay University, India
Ph.D. in Biochemistry, Bombay University, India
Type of Neoplasms
Head and Neck
Oral cavity
Gastrointestinal tract
Female genital system
Epidermis, Dermis, Appendages
  Last modified on : Mar 4, 2011
India Cancer Research Database has been developed by the Institute of Bioinformatics with funding from the Department of Biotechnology, Government of India.