Durga Prasad Mishra,                               Ph.D. 
                               
                              Scientist E-I  
                           
                         
                                  
         
                                                    
                                                    
                            Central Drug Research Institute 
                           
                                                                              
                            Endocrinology Division 
                           
                                                                              
                            Lucknow - 226 001                                 
                           
                                                    
                            Uttar Pradesh                                 
                           						  
                                                            
                           
                                                    
                            E-mail: dpm@cdri.res.in 
                           
                                                                              
                            Phone: +91-522-2612411-18, Extn. 4481 
                           
                                                    
                            Fax: +91-522-2623405  
                           
                  
                          
                               
                           
                          
                            URL:   http://www.cdriindia.org/dpmishra.htm  
                           
                          
                          						  
                              
                           
						  
	                                                       
                            Area of Specialization:  
                           
                          
                          
  
     
    Endocrinology 
   
     
                          
                        
                           
                           
                         
                         
                                                    
                                                    
                          
                             
                           
                                                    
                             Research Summary:  
                           
                                                    
                            
                                                                
                                   
                                  Epigenetic basis of male infertility 
                                 
                                                                
                                   
                                  Chemoresistance in cancers 
                                 
                                                                
                                   
                                  Effect of cancer chemotherapeutic drugs on spermatogonial stem cell niche, chromatin remodeling and epigenetic programming in male germ cells 
                                 
                                                                
                                   
                                  SERM induced apoptosis in cancer cells 
                                 
                                                                
                                   
                                  Mechanistic studies on novel proteasome inhibitors as anticancer drugs 
                                 
                                                                
                                   
                                  Endoplasmic reticulum stress mediated apoptosis in cerebral ischemia 
                                 
                                                            
 
                           
                          
                              
                           
                                                    
                            Publications:  
                           
                          
                            
	
		
			
				1. 
			
				Shaha, C., Tripathi, R. and Mishra, D. P.   Male germ cell apoptosis: regulation and biology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences.  2010. 365, 1501-1515. [PubMed]  
		 
		
			
				2. 
			
				Tripathi, R., Mishra, D. P.  and Shaha, C.  Male germ cell development: turning on the apoptotic pathways. Journal of Reproductive Immunology.  2009. 83, 31-35. [PubMed]  
		 
		
			
				3. 
			
				Nair, M., Nagamori, I., Sun, P., Mishra, D. P. , Rheaume, C., Li, B., Sassone-Corsi, P. and Dai, X.  Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation. Developmental Biology.  2008.  320, 446-455. [PubMed]  
		 
		
			
				4. 
			
				Mishra, D. P.  and Sassone-Corsi, P.  Epigenetic control in male germ cells: a transillumination-assisted microdissection method for the analysis of developmentally regulated events. Methods in Molecular Biology.  2008.  450, 119-126. [PubMed]  
		 
		
			
				5. 
			
				Mishra, D. P.  and Dhali, A.  Endotoxin induces luteal cell apoptosis through the mitochondrial pathway. Prostaglandins & Other Lipid Mediators.  2007.  83, 75-88. [PubMed]  
		 
		
			
				6. 
			
				Mishra, D. P. , Pal, R. and Shaha, C.  Changes in cytosolic Ca2+ levels regulate Bcl-xS and Bcl-xL expression in spermatogenic cells during apoptotic death. The Journal of Biological Chemistry.  2006.  281, 2133-2143. [PubMed]  
		 
		
			
				7. 
			
				Mishra, D. P.  and Shaha, C.  Estrogen-induced spermatogenic cell apoptosis occurs via the mitochondrial pathway: role of superoxide and nitric oxide. The Journal of Biological Chemistry.  2005. 280, 6181-6196. [PubMed]  
		 
	 
	 
  
                           
                         
                                                
 
                      
                          
                         
                     
                    
                        
                                      Last modified on : Mar 4, 2011