Sanjay Gupta, Ph.D.
Advanced Centre for Treatment Research and Education in Cancer
Gupta Lab
KS231, Tata Memorial Centre, Kharghar
Navi Mumbai - 410 210
Maharashtra
E-mail: guptalab@actrec.gov.in
Phone: +91-22-27405086, 27405000, Extn. 5393
Fax: +91-22-27405085
URL: http://www.actrec.gov.in/pi-webpages/SanjayGupta/Home.html
Area of Specialization:
Molecular Biology
Research Summary:
Chromatin structure and function during carcinogenesis and DNA damage
Publications:
1.
Pramod, K. S., Bharat, K. and Sanjay, G. Mass spectrometry-compatible silver staining of histones resolved on acetic acid-urea-Triton PAGE. Proteomics. 2009. 9, 2589-2592. [PubMed]
2.
Garg, R., Gupta, S. and Maru, G. B. Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis. 2008. 29, 1022-1032. [PubMed]
3.
Gupta, S. , Pathak, R. U. and Kanungo, M. S. DNA methylation induced changes in chromatin conformation of the promoter of the vitellogenin II gene of Japanese quail during aging. Gene. 2006. 377, 159-168. [PubMed]
4.
Bose, B., Gour, R. R., Motiwale, L., Gupta, S. and Rao, K. V. Hyperphosphorylation of extracellular regulated kinase 2 (ERK2) and inhibition of JNK2 phosphorylation are associated with increased S-phase during transformation of Syrian hamster embryo cells by Malachite Green. Cell Biology International. 2004. 28, 875-883. [PubMed]
5.
Gupta, S. , Sundarrajan, M. and Rao, K. V. Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins. Teratogenesis, Carcinogenesis, and Mutagenesis. 2003. Suppl 1, 301-312. [PubMed]
6.
Sundarrajan, M., Gupta, S. and Rao, K. V. Overexpression of cyclin D1 is associated with the decondensation of chromatin during den-induced sequential hepatocarcinogenesis. Cell Biology International. 2002. 26, 699-706. [PubMed]
7.
Mahendra, G., Gupta, S. and Kanungo, M. S. Effect of 17beta estradiol and progesterone on the conformation of the chromatin of the liver of female Japanese quail during aging. Archives of Gerontology and Geriatrics. 1999. 28, 149-158. [PubMed]
8.
Upadhyay, R., Gupta, S. and Kanungo, M. S. Trans-acting factors that interact with the proximal promoter sequences of ovalbumin gene are tissue-specific and age-related. Molecular and Cellular Biochemistry. 1999. 201, 65-72. [PubMed]
9.
Gupta, S. , Upadhyay, R. and Kanungo, M. S. Activation of vitellogenin II gene expression by steroid hormones in the old Japanese quail. Molecular Biology Reports. 1998. 25, 245-251. [PubMed]
10.
Kanungo, M. S., Gupta, S. and Upadhyay, R. Molecular biology of ageing. The Indian Journal of Medical Research. 1997. 106, 413-422. [PubMed]
11.
Upadhyay, R., Gupta, S. and Kanungo, M. S. Age-related changes in the ovalbumin gene of the Japanese quail. Biochemical and Biophysical Research Communications. 1996. 226, 356-361. [PubMed]
12.
Gupta, S., Upadhayay, R. and Kanungo, M. S. Interactions of trans-acting factor(s) with the estradiol response element and nuclear factor 1 of the vitellogenin II gene of Japanese quail. Biochemistry and Molecular Biology International. 1996. 39, 887-894. [PubMed]
13.
Gupta, S. and Kanungo, M. S. Modulation of vitellogenin II gene by estradiol and progesterone in the Japanese quail. Biochemical and Biophysical Research Communications. 1996. 222, 181-185. [PubMed]
Type of Neoplasms
Hepatobiliary system
Liver